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SGT-263 is a synthetic cannabinoid, part of a class of research chemicals designed to mimic the effects of naturally occurring cannabinoids by interacting with the endocannabinoid system, primarily the CB1 and CB2 receptors. Buy SGT-263 online.

Chemical Structure: SGT-263 typically features a central indole or indazole core with varying side chains, contributing to its potency and receptor selectivity. The precise chemical formula and structure may vary depending on the source of synthesis, but it is structurally related to other indole-based synthetic cannabinoids such as SGT-24 and SGT-25.

Mechanism of Action

• SGT-263 acts as a full agonist at CB1 and CB2 receptors.
• Activation of these receptors can lead to effects similar to Δ9-THC, including modulation of neurotransmitter release, analgesia, and psychoactive effects.
• Its receptor binding affinity is generally higher than THC, which may result in stronger or longer-lasting effects. Buy SGT-263 online.

Pharmacology

• Potency: SGT-263 is considered highly potent, with effects observed at microgram-level doses in in vitro studies.
• Metabolism: Like other synthetic cannabinoids, it is metabolized primarily by hepatic enzymes, producing metabolites that may retain some receptor activity.
• Duration: The onset and duration of effects are not fully characterized in humans, but analog studies suggest a rapid onset with variable duration depending on administration route.

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Research Applications

• Studying the endocannabinoid system and CB1/CB2 receptor pharmacology.
• Understanding structure-activity relationships (SAR) in synthetic cannabinoids.
• Screening for potential agonist or antagonist properties for pharmacological studies. Buy SGT-263 online.

Safety and Handling

• SGT-263 is considered a research-only chemical; human consumption is not recommended.
• Laboratory handling requires gloves, safety goggles, and fume hood use.
• Toxicological data are limited, and effects can be unpredictable due to high potency.

Legal Status

• The legality of SGT-263 varies by jurisdiction. In many regions, it is controlled under analog laws for synthetic cannabinoids. Always check local regulations before acquisition or research.

Analytical Detection

• SGT-263 can be detected using LC-MS/MS or GC-MS in biological samples.
• Standard analytical methods are being developed due to its structural similarity to other synthetic cannabinoids. Buy SGT-263 online.